About this blog

After seeing news articles say there was NO EVIDENCE that essential oils work for Ebola and hearing that the FDA has not approved any oils for any sort of disease, I decided to see what was out there and expose the essential oil industry. Instead, I found a mountain of peer reviewed studies for all kinds of serious diseases saying how well they work, even on Ebola! So, I decided to set up this blog to post a few studies a week to expose the real frauds and show the world what NO EVIDENCE looks like.
If you find value in my service, please donate to the blog since there is a cost to search and post these articles. I have waded through hundreds, if not thousands of difficult peer-reviewed articles to bring you those related to essential oils and ailments. I hope you find what you are looking for. I wish you great health, wealth and happiness!

(TIP: When looking for an article look in the Archive for titles but also use the Search Box because some articles may delay with say cancer in the title but also mention another disease so they may have tags that allow you to find them in the Search Box.)

Depression and Rosemary


"The present study clearly reinforces the notion that R. officinalis has a therapeutic potential as an antidepressant, since the effects of all fractions, isolated compounds and essential oil in the TST are similar to that produced by the classical antidepressant fluoxetine."

Antidepressant-like effects of fractions, essential oil, carnosol and betulinic acid isolated from Rosmarinus officinalis L.

Machado DG1, Cunha MP, Neis VB, Balen GO, Colla A, Bettio LE, Oliveira A, Pazini FL, Dalmarco JB, Simionatto EL, Pizzolatti MG, Rodrigues AL.

Abstract

The aim of this study was to investigate the antidepressant-like effect of fractions from Rosmarinus officinalis L.: ethyl acetate 1 and 2 (AcOEt1 and 2), hexane (HEX), ethanolic (ET), and essential oil-free (EOF) fractions, as well as essential oil, the isolated compounds carnosol and betulinic acid in the tail suspension test, a predictive test of antidepressant activity. Swiss mice were acutely administered by oral route (p.o.) with fractions, essential oil or isolated compounds, 60 min before the tail suspension test or open-field test. All of them produced a significant antidepressant-like effect: AcOEt1, ET, EOF fractions and essential oil (0.1-100mg/kg, p.o); HEX (0.1-10mg/kg, p.o) and AcOEt2 fraction (0.1-1mg/kg, p.o), carnosol (0.01-0.1mg/kg, p.o.) isolated from the HEX fraction and betulinic acid (10mg/kg, p.o.), isolated from the AcOEt1 and AcOEt2 fractions. No psychostimulant effect was shown in the open-field test, indicating that the effects in the tail suspension test are specific. This study suggests that carnosol and betulinic acid could be responsible for the anti-immobility effect of extracts from R. officinalis.
Copyright © 2012 Elsevier Ltd. All rights reserved.
PMID:
 
23122155
 
[PubMed - indexed for MEDLINE]


Link to full article here.


You are reading The Essential Oil Skeptic.
Subscribe by email for free for a limited time to see more scientific studies on essential oils?
http://essentialoilskeptic.com
share: pinterest
Labels: , , , , ,
 
site design by designer blogs