About this blog

After seeing news articles say there was NO EVIDENCE that essential oils work for Ebola and hearing that the FDA has not approved any oils for any sort of disease, I decided to see what was out there and expose the essential oil industry. Instead, I found a mountain of peer reviewed studies for all kinds of serious diseases saying how well they work, even on Ebola! So, I decided to set up this blog to post a few studies a week to expose the real frauds and show the world what NO EVIDENCE looks like.
If you find value in my service, please donate to the blog since there is a cost to search and post these articles. I have waded through hundreds, if not thousands of difficult peer-reviewed articles to bring you those related to essential oils and ailments. I hope you find what you are looking for. I wish you great health, wealth and happiness!

(TIP: When looking for an article look in the Archive for titles but also use the Search Box because some articles may delay with say cancer in the title but also mention another disease so they may have tags that allow you to find them in the Search Box.)

Cancer and Cinnamon Bark Oil

Conclusion

Our study suggests that anti-tumor effect of cinnamon extracts is directly linked with enhanced pro-apoptotic activity and inhibition of NFκB and AP1 activities and their target genes in vitro and in vivo mouse melanoma model. Hence, further elucidation of active components of cinnamon extract could lead to development of potent anti-tumor agent or complementary and alternative medicine for the treatment of diverse cancers.

Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1

Ho-Keun Kwon1, Ji-Sun Hwang1, Jae-Seon So1, Choong-Gu Lee1, Anupama Sahoo1, Jae-Ha Ryu1, Won Kyung Jeon2, Byoung Seob Ko2, Chang-Rok Im3, Sung Haeng Lee4, Zee Yong Park1 and Sin-Hyeog Im1*
Author Affiliations



1School of Life Sciences and Immune Synapse Research Center, Gwangju Institute of Science and Technology (GIST), 1 Oryong-dong, Puk-ku, Gwangju 500-712, Republic of Korea
2Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of Korea
3Global leader program, Bugil Academy, Cheonan, Gyeonggido 330-941, Republic of Korea
4Chosun University School of Medicine, Gwangju 501-759, Republic of Korea
For all author emails, please log on.



BMC Cancer 2010, 10:392  doi:10.1186/1471-2407-10-392

Received:10 December 2009
Accepted:24 July 2010
Published:24 July 2010
© 2010 Kwon et al; licensee BioMed Central Ltd. 
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background

Cinnamomum cassia bark is the outer skin of an evergreen tall tree belonging to the family Lauraceae containing several active components such as essential oils (cinnamic aldehyde and cinnamyl aldehyde), tannin, mucus and carbohydrate. They have various biological functions including anti-oxidant, anti-microbial, anti-inflammation, anti-diabetic and anti-tumor activity. Previously, we have reported that anti-cancer effect of cinnamon extracts is associated with modulation of angiogenesis and effector function of CD8+ T cells. In this study, we further identified that anti-tumor effect of cinnamon extracts is also link with enhanced pro-apoptotic activity by inhibiting the activities NFκB and AP1 in mouse melanoma model.

share: pinterest
Labels: , , , , , , ,
 
site design by designer blogs