'Thus, scent of lavender oil and
its active component, linalool, affect autonomic nerves, suppress
lipolysis through a histaminergic response, and enhance appetite and
body weight.'
Olfactory stimulation with scent of lavender oil affects autonomic nerves, lipolysis and appetite in rats.
Abstract
In
a previous study, we presented evidence that scent of grapefruit oil
excites sympathetic nerves innervating white and brown adipose tissues
and the adrenal gland, inhibits the vagal nerve innervating the stomach,
increases lipolysis and heat production (energy consumption), and
reduces appetite and body weight. Here, we examined the effects of
olfactory stimulation with scent of lavender oil (SLVO) in rats and
observed that in contrast to grapefruit oil, it inhibits the sympathetic
nerves innervating the white and brown adipose tissues and adrenal
gland and excites the parasympathetic gastric nerve. Local anesthesia of
the nasal mucosa with xylocaine or anosmic treatment using ZnSO(4)
eliminated the autonomic changes caused by SLVO. Moreover, stimulation
with SLVO lowered the plasma glycerol level, and treatment with either
ZnSO(4) or an intracranial injection of thioperamide, a histamine H3
receptor-antagonist, abolished SLVO-mediated glycerol decline.
Furthermore, a 15-min daily exposure to SLVO increased food intake and
body weight. Finally, linalool, a component of lavender oil, induced
responses similar to those caused by SLVO, and the glycerol response to
linalool was eliminated by thioperamide.
Want to see more scientific studies on essential oils?
www.essentialoilskeptic.com
Neurosci Lett. 2005 Jul 22-29;383(1-2):188-93.
Olfactory stimulation with scent of lavender oil affects autonomic nerves, lipolysis and appetite in rats.
Abstract
In
a previous study, we presented evidence that scent of grapefruit oil
excites sympathetic nerves innervating white and brown adipose tissues
and the adrenal gland, inhibits the vagal nerve innervating the stomach,
increases lipolysis and heat production (energy consumption), and
reduces appetite and body weight. Here, we examined the effects of
olfactory stimulation with scent of lavender oil (SLVO) in rats and
observed that in contrast to grapefruit oil, it inhibits the sympathetic
nerves innervating the white and brown adipose tissues and adrenal
gland and excites the parasympathetic gastric nerve. Local anesthesia of
the nasal mucosa with xylocaine or anosmic treatment using ZnSO(4)
eliminated the autonomic changes caused by SLVO. Moreover, stimulation
with SLVO lowered the plasma glycerol level, and treatment with either
ZnSO(4) or an intracranial injection of thioperamide, a histamine H3
receptor-antagonist, abolished SLVO-mediated glycerol decline.
Furthermore, a 15-min daily exposure to SLVO increased food intake and
body weight. Finally, linalool, a component of lavender oil, induced
responses similar to those caused by SLVO, and the glycerol response to
linalool was eliminated by thioperamide. Thus, scent of lavender oil and
its active component, linalool, affect autonomic nerves, suppress
lipolysis through a histaminergic response, and enhance appetite and
body weight.
- PMID:
- 15878236
- [PubMed - indexed for MEDLINE]
Want to see more scientific studies on essential oils?
www.essentialoilskeptic.com
