About this blog

After seeing news articles say there was NO EVIDENCE that essential oils work for Ebola and hearing that the FDA has not approved any oils for any sort of disease, I decided to see what was out there and expose the essential oil industry. Instead, I found a mountain of peer reviewed studies for all kinds of serious diseases saying how well they work, even on Ebola! So, I decided to set up this blog to post a few studies a week to expose the real frauds and show the world what NO EVIDENCE looks like.
If you find value in my service, please donate to the blog since there is a cost to search and post these articles. I have waded through hundreds, if not thousands of difficult peer-reviewed articles to bring you those related to essential oils and ailments. I hope you find what you are looking for. I wish you great health, wealth and happiness!

(TIP: When looking for an article look in the Archive for titles but also use the Search Box because some articles may delay with say cancer in the title but also mention another disease so they may have tags that allow you to find them in the Search Box.)

MRSA

Effect of Lippia origanoides H.B.K. essential oil in the resistance to aminoglycosides in methicillin resistant Staphylococcus aureus

Abstract

Introduction

Methicillin resistant Staphylococcus aureus (MRSA) is a common cause of hospital and community-acquired infections worldwide.

Methodology

In this study the essential oil of Lippia origanoides H.B.K., Verbenaceae, was assayed for its modifying drug activity against a MRSA strain by microdilution method.

Results

A significant potentiating effect between this oil and the aminoglycosides tested was verified. The MIC values for neomycin and amikacin alone were 2500 and 788 μg/mL, respectively. These were reduced to 248 and 78 μg/mL when they were associated with the essential oil against MRSA strain. A similar synergism was observed when the oil was changed for chlorpromazine, an efflux pump inhibitor, suggesting the involvement of resistance mediated by efflux system.

Conclusions

The results indicated that L. origanoides H.B.K. can be a source of secondary metabolites to be used in association with aminoglycosides in the antibiotic chemotherapy against illnesses caused by MRSA.

Go to the full article

Keywords

  • MRSA; 
  • Staphylococcus aureus; 
  • Antibiotic activity; 
  • Synergism; 
  • Lippia origanoides
Corresponding author at: Laboratório de Microbiologia e Biologia Molecular, Departamento de Química Biológica, Universidade Regional do Cariri – URCA, Rua Cel. Antonio Luis 1161, Pimenta 63105-000, Crato, CE, Brazil. Tel.: +55 88 31021212; fax: +55 88 31021291.
Copyright © 2014 Elsevier GmbH. All rights reserved.

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