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After seeing news articles say there was NO EVIDENCE that essential oils work for Ebola and hearing that the FDA has not approved any oils for any sort of disease, I decided to see what was out there and expose the essential oil industry. Instead, I found a mountain of peer reviewed studies for all kinds of serious diseases saying how well they work, even on Ebola! So, I decided to set up this blog to post a few studies a week to expose the real frauds and show the world what NO EVIDENCE looks like.
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Yellow Fever/Hemorrhagic Fever and Oregano, Mugwort and various Verbenas

The essential oils evaluated in the study showed antiviral activities against YFV.(Yellow Fever Virus) The mode of action seems to be direct virus inactivation.

Inhibitory effect of essential oils obtained from plants grown in Colombia on yellow fever virus replication in vitro

Rocío Meneses12*Raquel E Ocazionez12Jairo R Martínez13 and Elena E Stashenko13

1Centro Nacional de Investigaciones para la Agroindustrialización de Especies Vegetales Aromáticas y Medicinales Tropicales, CENIVAM. Universidad Industrial de Santander, Bucaramanga, Colombia
2Centro de Investigaciones en Enfermedades Tropicales, CINTROP, Laboratorio de Arbovirus, Piedecuesta, Colombia
3Centro de Investigación en Biomoléculas, CIBIMOL, Bucaramanga, Colombia
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Annals of Clinical Microbiology and Antimicrobials 2009, 8:8  doi:10.1186/1476-0711-8-8

The electronic version of this article is the complete one and can be found online at: http://www.ann-clinmicrob.com/content/8/1/8

Received:25 November 2008
Accepted:6 March 2009
Published:6 March 2009
© 2009 Meneses et al; licensee BioMed Central Ltd. 
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.



An antiviral drug is needed for the treatment of patients suffering from yellow fever. Several compounds present in plants can inactive in vitro a wide spectrum of animal viruses.


In the present study the inhibitory effect of essential oils of Lippia alba, Lippia origanoides, Oreganum vulgare and Artemisia vulgaris on yellow fever virus (YFV) replication was investigated.


The cytotoxicity (CC50) on Vero cells was evaluated by the MTT reduction method. The minimum concentration of the essential oil that inhibited virus titer by more than 50% (MIC) was determined by virus yield reduction assay. YFV was incubated 24 h at 4°C with essential oil before adsorption on Vero cell, and viral replication was carried out in the absence or presence of essential oil. Vero cells were exposed to essential oil 24 h at 37°C before the adsorption of untreated-virus.


The CC50 values were less than 100 μg/mL and the MIC values were 3.7 and 11.1 μg/mL. The CC50/MIC ratio was of 22.9, 26.4, 26.5 and 8.8 for L. alba, L origanoides, O. vulgare and A. vulgaris, respectively. The presence of essential oil in the culture medium enhances the antiviral effect: L. origanoides oil at 11.1 μg/mLproduced a 100% reduction of virus yield, and the same result was observed with L. alba, O. vulgare and A. vulgaris oils at100 μg/mL. No reduction of virus yield was observed when Vero cells were treated with essential oil before the adsorption of untreated-virus.


The essential oils evaluated in the study showed antiviral activities against YFV. The mode of action seems to be direct virus inactivation.

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